Endocrine Abstracts

IntroductionThe mechanism by which hypertrophy of skeletal muscle occurs in response to anabolic androgens is incompletely understood. This study used a cell culture model of human skeletal muscle-derived cells, with samples obtained from consenting subjects and local ethics committee approval. The objective was to determine changes in myogenicity upon exposure to exogenous androgen +/− IGF-1 and to see whether an additive effect would be observed....